Defense attorney Theodore Simon said the fact that there is no physical evidence tying Amanda Knox to the 2007 murder of Meredith Kercher should tell the jury "unassailably that she is innocent."

“There was no hair, fiber, footprint, shoe print, handprint, palm print, fingerprint, sweat, saliva, DNA of Amanda Knox in the room where Meredith Kercher was killed,” attorney Theodore Simon told TODAY’s Savannah Guthrie. “That in and of itself tells you unassailably that she is innocent.”

Kercher and Knox were roommates studying abroad when the murder took place. 

After spending four years in an Italian prison, Knox was released on appeal in 2011. The Italian Supreme Court recently dismissed the appellate court's ruling, reviving the case.

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